Actor Jake Gyllenhaal collaborated with “Stand Up 2 Cancer” and Major League Baseball for a new PSA, which aired during the All-Star Game on Tuesday.

It draws parallels between victory in baseball and the triumph of beating cancer through teamwork and collaboration. Watch the PSA here.

“Stand Up to Cancer Event” will air live and commercial-free on Sept. 10, on NBC, ABC, CBS, FOX, as well as VH1, HBO, Showtime and others.